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  • 产品名称: EZM0414
  • 产品货号: CST9969
  • 货期: 现货
  • 价格与订购: 2800
  • 数量:
    库存: 5
  • 规格: 1mg
  • 产品信息
  • 如何订购
    产品描述
    EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 with IC50 of 18 nM in SETD2 biochemical assay and IC50 of 34 nM in a cellular assay. EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma [1].
    Cas No.
    2411748-50-8
    分子式
    C22H29FN4O2
    分子量
    400.49
    参考文献
    [1]Jennifer Totman, et al. Pharmacologic Inhibition of the Histone Methyltransferase SETD2 with EZM0414 As a Novel Therapeutic Strategy in Relapsed or Refractory Multiple Myeloma and Diffuse Large B-cell Lymphoma.
    储存和溶解度
    DMSO:115 mg/mL (287.15 mM),ultrasonic and warming and heat to 60°C
    Powder: -20°C for 3 years
    In solvent: -80°C for 2 years
    Note
    For research use only .