Anti NRP1 polyclonal antibody
Produced in rabbits immunized with purified,Recombinant Human NRP1 protein
Recognizes Human NRP1 protein
Neuropilin-1,Vascular endothelial cell growth factor 165 receptor,CD304,VEGF165R
Neuropilin-1 (NRP1) is a a 130–140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
Human,other species was not test
Recombinant protein of human NRP1(Phe22-Lys644).
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
PBS,pH7.4,containing 0.05% proclin300,50% glycerol.