Anti CD147 polyclonal antibody
Produced in rabbits immunized with purified,Recombinant Human CD147 protein
Recognizes Human CD147 protein
Collagenase stimulatory factor,OK blood group antigen,Leukocyte activation antigen M6,Tumor cell-derived collagenase stimulatory factor,Basigin,Extracellular matrix metalloproteinase inducer,CD147,TCSF,EMMPRIN,5F7,BSG
BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
Human,other species was not test
Recombinant protein of human CD147(Ala22-Ala207).
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.