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  • 产品名称: Anti SARS-CoV-2 (2019-nCoV) NSP1 polyclonal antibody
  • 产品货号: CSP249
  • 货期: 现货
  • 价格与订购: 1300
  • 数量:
    库存: 100
  • 规格: 50μg 100μg 1mg
  • 产品信息
  • 如何订购
    产品名称(Product name)
    Anti SARS-CoV-2 (2019-nCoV) NSP1 polyclonal antibody
    货号(Catalog#)
    CSP249
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    Accession #
    P0DTC1
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    描述(description)
    Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP1
    别名(Alternative names)
    ORF1a polyprotein,Non-structural protein 1,Leader protein,Replicase polyprotein 1a
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    特异性(Spcificty)
    Recognizes SARS-CoV-2 NSP1
    亚型(Isotype)
    IgG
    宿主(Host)
    Rabbit
    克隆性(Clonality)
    Polyclonal
    偶连物(Conjugation)
    Unconjugate
    种属反应性(Species reactivity)
    Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
    免疫原(Immunogen)
    Recombinant SARS-CoV-2 NSP1(Met1-Gly180)
    背景(Background)
    The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close association with cellular membranes. Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.icon
    状态(Form)
    Liquidicon
    储存溶液(Buffer)
    PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
    浓度(Concentration)
    0.55mg/mliconicon
    分子量(MW)
    20kDa
    应用实验及稀释比例(Dilution Range)
    Elisa:1:4000~1:8000
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    产品实验图片(Tested Picture)icon

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    Note
    For research use only .