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Anti SARS-CoV-2 (2019-nCoV) NSP1 polyclonal antibody
浏览量:
产品名称:

Anti SARS-CoV-2 (2019-nCoV) NSP1 polyclonal antibody

NO.
114
货号:
CSP249
中文名称
新冠相关抗体
英文名词
Anti SARS-CoV-2 (2019-nCoV) NSP1 polyclonal antibody
CAS号
/
产品货号:
CSP249
货期:
现货
价格与订购:
1300.00
数量
-
+
库存:
300
没有此类产品
产品信息
如何订购
产品名称(Product name)icon
Anti SARS-CoV-2 (2019-nCoV) NSP1 polyclonal antibody
货号(Catalog#)
icon
CSP249
iconiconicon
Accession #
icon
P0DTC1
icon
描述(description)icon
Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP1
别名(Alternative names)icon
ORF1a polyprotein,Non-structural protein 1,Leader protein,Replicase polyprotein 1a
稳定性&储存(Stability &Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
特异性(Spcificty)icon
Recognizes SARS-CoV-2 NSP1
亚型(Isotype)icon
IgG
宿主(Host)icon
Rabbit
克隆性(Clonality)icon
Polyclonal
偶连物(Conjugation)icon
Unconjugate
种属反应性(Species reactivity)icon
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
免疫原(Immunogen)icon
Recombinant SARS-CoV-2 NSP1(Met1-Gly180)
背景(Background)icon
The Severe Acute Respiratory Syndrome (SARS) Coronavirus (CoV) is an enveloped, positive-stranded RNA viruses that can cause a severe respiratory disease. Its genome consists of a ∼30 kb linear, non-segmented, capped, polycistronic, polyadenylated RNA molecule, the first two-third of which is directly translated into two large polyproteins. These two polypeptides are processed into 16 non-structural proteins (nsps), forming the replicase complex, which is active in the cytoplasm in close association with cellular membranes. Nsp1 was proved to be able to suppress host gene expression by promoting host mRNA degradation and was involved in cellular chemokine deregulation. This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent signaling. Thus, nsp1 is a promising target for drugs, as inhibition of nsp1 would make SARS-CoV more susceptible to the host antiviral defenses.icon
状态(Form)icon
Liquidicon
储存溶液(Buffer)
icon
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
浓度(Concentration)icon
0.55mg/mliconicon
分子量(MW)icon
20kDa
应用实验及稀释比例(Dilution Range)
icon
Elisa:1:4000~1:8000
iconicon
产品实验图片(Tested Picture)iconicon

iconiconicon
Note
icon
For research use only .
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