Anti SARS-CoV-2 (2019-nCoV) S1 Protein polyclonal antibody
Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 S1 Protein
Spike glycoprotein,E2,Peplomer protein,Spike protein S1,S
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Recognizes SARS-CoV-2 S1 Protein
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
Recombinant SARS-CoV-2 S1 Protein(Val16-Gln677)
Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein. Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry. Can be alternatively processed by host furin . Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.icon
PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.