搜索

159-2642-3062

服务热线(工作日:9:00-17:30)

武汉科斯坦生物科技有限公司

热搜词:燕窝酸,不饱和脂肪酸,神经酰胺,花青素,黄酮,皂苷

Wuhan Chemstan Biotechnology Co., Ltd.

武汉科斯坦生物科技有限公司

代谢组学

科研服务

抗体/蛋白

地       址:武汉市东湖新技术开发区高新大道666号,武汉

                 国家生物产业基地B、C、D区研发楼C1栋
产品销售:15926423062
技术服务:18971263062                                             
E - mail :
info@chemstan.com       
邮       编:430075

化合物单体

科斯坦生物(Chemstan)所有产品和服务仅用于科学研究,不为任何个人或者非科研性质的用途提供产品和服务。

Copyright @ 武汉科斯坦生物科技有限公司.All rights reserved

网站建设:中企动力武汉鄂ICP备19006850号-1

>
>
>
Anti SMAD4(R361S) Mouse Monoclonal Antibody
浏览量:
产品名称:

Anti SMAD4(R361S) Mouse Monoclonal Antibody

NO.
货号:
CST26423
中文名称
Anti SMAD4(R361S) Mouse Monoclonal Antibody
英文名词
Anti SMAD4(R361S) Mouse Monoclonal Antibody
CAS号
产品货号:
CST26423
货期:
现货
价格与订购:
4800.00
数量
-
+
库存:
5
没有此类产品
产品信息
如何订购
Catalog Numbericon
CST26423
Gene Symbolicon
SMAD4, DPC4, JIP, MADH4, MYHRS
iconicon
Descriptionicon
 Anti SMAD4(R361S) Mouse Monoclonal Antibody
Backgroundicon
 SMAD4 family member 4, also known as SMAD4, is a protein that in human is encoded by the SMAD4 gene. It is often found mutated in many cancers. It acts as a tumor suppressor that functions in the regulation of the TGF-? signal transduction pathway, which negatively regulates growth of epithelial cells and the extracellular matrix (ECM). SMAD4 alterations have been found in multiploid colorectal cancer and pancreatic carcinoma. It is found inactivated in at least 50% of pancreatic cancers. It is also found mutated in the autosomal dominantdisease juvenile polyposis syndrome (JPS).
Immunogenicon
A synthetic peptide from the internal region of SMAD4 which includes the mutation of R361S, human origin.
Applicationsicon
ELISA, WB, IHC
Recommended Dilutionsicon
ELISA: 1:1000-1:2000 
WB: 1:500-1:1000 
IHC: 1:50-1:100
Concentrationicon
1 mg/ml
Hosticon
mouse
icon
Formaticon
Liquid
Clonalityicon
Monoclonal
Purityicon
Purified from ascites
Preservativeicon
no
Constituentsicon
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivityicon
Recognizes E545G mutant, but not wild-type PIK3CA of vertebrates.
Immunoprecipitation/Western Blot
icon

Western blot analysis of recombinant SMAD4(R361S) and wildtype proteins. Purified His-tagged SMAD4(R361S) protein (lane1) and corresponding wild-type protein (lane2) were blotted with Anti SMAD4(R361S) monoclonal antibody (Cat. #26423).
icon
Immunofluorescence: icon

Immunofluorescence of cells expressing SMAD4 proteins with Anti SMAD4(R361S) antibody. HEK293T cells were transfected with pCDNA3-GFP SMAD4(R361S) plasmid pCDNA3-GFP SMAD4(WT) plasmid, pCDNA3-GFP SMAD4(R361H) plasmid or pCDNA3-GFP SMAD4(R361C) plasmid, then fixed and stained with Anti SMAD4(R361S) monoclonal antibody (Cat. #26423).
iconicon
Storage Conditionsicon
Store at -20°C. Avoid freeze / thaw cycles
iconiconicon
Noteicon
For Research Use Only.
未找到相应参数组,请于后台属性模板中添加
暂未实现,敬请期待
暂未实现,敬请期待
上一篇
下一篇