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武汉科斯坦生物科技有限公司
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代谢组学
科研服务
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地 址:武汉市东湖新技术开发区高新大道666号,武汉
国家生物产业基地B、C、D区研发楼C1栋
产品销售:15926423062
技术服务:18971263062
E - mail :info@chemstan.com
邮 编:430075
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产品名称:
Anti RET(C634Y) Mouse Monoclonal Antibody
NO.
货号:
CST26146
中文名称
Anti RET(C634Y) Mouse Monoclonal Antibody
英文名词
Anti RET(C634Y) Mouse Monoclonal Antibody
CAS号
产品货号:
CST26146
货期:
现货
价格与订购:
4800.00
数量:
-
+
库存:
5
产品信息
如何订购
Catalog Numbericon
CST26146
Gene Symbolicon
RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B
iconicon
Descriptionicon
Anti RET(C634Y) Mouse Monoclonal Antibody
Backgroundicon
RET protein is encoded by the RET proto- oncogene. It is a receptor tyrosine kinase. RET loss of function mutations are associated with the development of Hirschsprung’s disease, while gain of function mutations are associated with development of various types of human cancer, including medullary thyroid carcinoma, multiple endocrine neoplasias type 2A and 2B, pheochromocytoma and parathyroid hyperplasia.
Immunogenicon
A synthetic peptide from the internal region of RET which includes the mutation of C634Y, human origin.
Applicationsicon
ELISA, WB, IHC
Recommended Dilutionsicon
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentrationicon
0.5 mg/ml
Hosticon
mouse
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Formaticon
Liquid
Clonalityicon
Monoclonal
Purityicon
Purified from ascites
Preservativeicon
no
Constituentsicon
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivityicon
Recognizes C634Y mutant, but not wild-type RET of vertebrates.
Immunoprecipitation/Western Blot
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icon

Western blot analysis of recombinant RET(C634Y) and wildtype proteins. Purified His-tagged RET(C634Y) protein (lane1) and corresponding wild-type protein (lane2) were blotted with Anti RET(C634Y) monoclonal antibody (Cat. #26146).
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Immunofluorescence: icon

Immunofluorescence of cells expressing RET proteins with Anti RET(C634Y) antibody. HEK293T cells were transfected with pCDNA3-GFP RET(WT) plasmid (left column) or pCDNA3-GFP RET(C634Y) plasmid (right column), then fixed and stained with Anti RET(C634Y) monoclonal antibody (Cat. #26146).
iconiconicon
Storage Conditionsicon
Store at -20°C. Avoid freeze / thaw cycles
iconiconiconicon
Noteicon
For Research Use Only.
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