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武汉科斯坦生物科技有限公司

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Anti RAS(A146P) Mouse Monoclonal Antibody
浏览量:
产品名称:

Anti RAS(A146P) Mouse Monoclonal Antibody

NO.
货号:
CST26478
中文名称
Anti RAS(A146P) Mouse Monoclonal Antibody
英文名词
Anti RAS(A146P) Mouse Monoclonal Antibody
CAS号
产品货号:
CST26478
货期:
现货
价格与订购:
4800.00
数量
-
+
库存:
5
没有此类产品
产品信息
如何订购
Catalog Numbericon
CST26478
Gene Symbolicon
H-Ras; K-Ras; N-Ras
iconicon
Descriptionicon
Anti RAS(A146P) Mouse Monoclonal Antibody
Backgroundicon
The A146P mutation of KRas results in an amino acid substitution at position 146, from an alanine to a threonine. KRAS encodes a protein that is a member of the small GTPase superfamily. Ras A146P mutation results in decreased GTPase activity and constitutive signaling. It can be found in many tumors, such as lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Immunogenicon
A synthetic peptide from the internal region of Ras which includes the mutation of A146P, human origin.
Applicationsicon
 ELISA, IF, IHC
Recommended Dilutionsicon
ELISA: 1:1000-1:5000 
IF: 1:50-1:100 
IHC: 1:50-1:100
Concentrationicon
1 mg/ml
Hosticon
mouse
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Formaticon
Liquid
Clonalityicon
Monoclonal
Purityicon
Purified from ascites
Preservativeicon
no
Constituentsicon
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivityicon
Recognizes A146P mutant, but not wild-type RAS of vertebrates.    
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Immunofluorescence: icon

Immunofluorescence of cells expressing KRas proteins with anti-KRAS(A146P) antibody. HEK293T cells were transfected with pCDNA3-GFP-KRAS(A146P) plasmid , pCDNA3-GFP KRas(WT) plasmid, pCDNA3-GFP KRas(A146V) plasmid or pCDNA3-GFP KRas(A146T) plasmid, then fixed and stained with anti-KRAS(A146P) monoclonal antibody (Cat. #26478).
iconicon
Storage Conditionsicon
Store at -20°C. Avoid freeze / thaw cycles
iconiconicon
Noteicon
For Research Use Only.
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