![]() |
Amily |
![]() |
Emily |
![]() |
Lily |
武汉科斯坦生物科技有限公司
-
在线咨询
-
官方邮箱
-
微信下单
-
回到顶部
代谢组学
科研服务
抗体/蛋白
地 址:武汉市东湖新技术开发区高新大道666号,武汉
国家生物产业基地B、C、D区研发楼C1栋
产品销售:15926423062
技术服务:18971263062
E - mail :info@chemstan.com
邮 编:430075
化合物单体
科斯坦生物(Chemstan)所有产品和服务仅用于科学研究,不为任何个人或者非科研性质的用途提供产品和服务。
Copyright @ 武汉科斯坦生物科技有限公司.All rights reserved
网站建设:中企动力武汉鄂ICP备19006850号-1
浏览量:
产品名称:
Research Grade Fianlimab (弗安利单抗 )
NO.
581
货号:
CSD00632
中文名称
弗安利单抗
英文名词
Research Grade Fianlimab
CAS号
2126132-98-5
产品货号:
CSD00632
货期:
现货
价格与订购:
2480.00
数量:
-
+
库存:
100
产品信息
如何订购
货号(Catalog No.)icon
CSD00632
通用名INNicon
Fianlimab
纯度(Purity)icon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
别名(Alternative names)icon
REGN3767
靶点;物种(Specificity target name;species)icon
LAG3/CD223[Homo sapiens]
活性研究(体外/体内研究)(Activity in vitro)icon
Complement-dependent cytotoxicity(CDC), complement-dependent cellular cytotoxicity(CDCC), antibody-dependent cytotoxicity (ADCC) as well as the induction of apoptosis have been claimed to be responsible for the efficacy of rituximab. Rituximab can induce death of malignant B cell lines in vitro. The strength of this effect varies considerably between target cell lines. Changes that have been identified in response to rituximab in vitro include inhibition of p38 mitogen-activated protein kinase, NF-κB, extracellular signal-regulated kinase 1/2 (ERK 1/2) and AKT antiapoptotic survival pathways. Rituximab is highly efficient at mediating CMC(complement dependent cytotoxicity) of various B cell lines as well as fresh malignant B cell samples. CD20-binding capacity of rituximab is dose-dependent.
种类(Species)icon
Homo sapiens
受体鉴定(Receptor identification)icon
IgG4-kappa
CASicon
2126132-98-5
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
上一篇
Research Grade Epcoritamab (艾可瑞妥单抗 )
Research Grade Gatralimab (格曲利单抗 )
下一篇