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武汉科斯坦生物科技有限公司
热搜词：燕窝酸，不饱和脂肪酸，神经酰胺，花青素，黄酮，皂苷
Wuhan Chemstan Biotechnology Co., Ltd.
武汉科斯坦生物科技有限公司
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产品名称：
Research Grade Fianlimab (弗安利单抗 )
NO.
581
货号：
CSD00632
中文名称
弗安利单抗
英文名词
Research Grade Fianlimab
CAS号
2126132-98-5
产品货号：
CSD00632
货期：
现货
价格与订购：
2480.00
数量：
-
+
库存：
100
产品信息
如何订购
货号（Catalog No.）icon
CSD00632
通用名INNicon
Fianlimab
纯度(Purity)icon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
别名(Alternative names)icon
REGN3767
靶点;物种(Specificity target name;species)icon
LAG3/CD223[Homo sapiens]
活性研究（体外/体内研究）(Activity in vitro)icon
Complement-dependent cytotoxicity(CDC), complement-dependent cellular cytotoxicity(CDCC), antibody-dependent cytotoxicity (ADCC) as well as the induction of apoptosis have been claimed to be responsible for the efficacy of rituximab. Rituximab can induce death of malignant B cell lines in vitro. The strength of this effect varies considerably between target cell lines. Changes that have been identified in response to rituximab in vitro include inhibition of p38 mitogen-activated protein kinase, NF-κB, extracellular signal-regulated kinase 1/2 (ERK 1/2) and AKT antiapoptotic survival pathways. Rituximab is highly efficient at mediating CMC(complement dependent cytotoxicity) of various B cell lines as well as fresh malignant B cell samples. CD20-binding capacity of rituximab is dose-dependent.
种类(Species)icon
Homo sapiens
受体鉴定(Receptor identification)icon
IgG4-kappa
CASicon
2126132-98-5
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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