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武汉科斯坦生物科技有限公司

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Research Grade Ocaratuzumab ( 奥卡妥珠单抗 )
浏览量:
产品名称:

Research Grade Ocaratuzumab ( 奥卡妥珠单抗 )

NO.
285
货号:
CSD00293
中文名称
奥卡妥珠单抗
英文名词
Research Grade Ocaratuzumab
CAS号
1169956-08-4
产品货号:
CSD00293
货期:
现货
价格与订购:
2480.00
数量
-
+
库存:
100
没有此类产品
产品信息
如何订购
货号(Catalog No.)icon
CSD00293
通用名INNicon
Ocaratuzumab
纯度(Purity)icon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
别名(Alternative names)icon
AME-133v,LY2469298
靶点;物种(Specificity target name;species)icon
MS4A1/CD20[Homo sapiens]
活性研究(体外/体内研究)(Activity in vitro)icon
Complement-dependent cytotoxicity(CDC), complement-dependent cellular cytotoxicity(CDCC), antibody-dependent cytotoxicity (ADCC) as well as the induction of apoptosis have been claimed to be responsible for the efficacy of rituximab. Rituximab can induce death of malignant B cell lines in vitro. Th strength of this effect varies considerably between target cell lines. Changes that have been identified in response to rituximab in vitro include inhibition of p38 mitogen-activated protein kinase, NF-κB, extracellular signal-regulated kinase 1/2 (ERK 1/2) and AKT antiapoptotic survival pathways. Rituximab is highly efficient at mediating CMC(complement dependent cytotoxicity) of various B cell lines as well as fresh malignant B cell samples. CD20-binding capacity of rituximab is dose-dependentv.
种类(Species)icon
Humanized
受体鉴定(Receptor identification)icon
IgG1-kappa
CASicon
1169956-08-4
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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