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  • 产品名称: Research Grade Fasinumab ( 法司努单抗 )
  • 产品货号: CSD00286
  • 货期: 现货
  • 价格与订购: 2480
  • 数量:
    库存: 100
  • 规格: 100μg
  • 产品信息
  • 如何订购
    货号(Catalog No.)
    CSD00286
    通用名INN
    Fasinumab
    纯度(Purity)
    >95%
    浓度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    产品描述(Description)
    Fasinumab has been used in trials studying the basic science and treatment of Sciatica, Back Pain, Low Back Pain, Osteoarthritis, Hip, and Abdominal Pain Upper, among others.
    别名(Alternative names)
    REGN475,SAR164877
    靶点;物种(Specificity target name;species)
    NGF/NGFB [Homo sapiens]
    活性研究(体外/体内研究)(Activity in vitro)
    Ro 08-2750 binds to the NGF dimer thereby probably inducing a change in its conformation such that NGF cannot bind to p75NTR anymore.
    Ro 08-2750 (10 nM) completely rescues cells from undergoing NGF-induced SK-N-MC 10^3 cells death.Ro 08-2750 (5-10 μM; 8 hours) increases differentiation and apoptosis in myeloid leukemia cells.Ro 08-2750 inhibits survival of human AML lines and patient cells.Ro 08-2750 inhibits MSI2 RNA-binding and alters MSI2 gene signature.
    种类(Species)
    Homo sapiens
    受体鉴定(Receptor identification)
    IgG4-kappa
    CAS
    1190239-42-9
    存储条件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .