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  • 产品名称: Anti SARS-CoV-2(2019-nCoV) NSP3 polyclonal antibody
  • 产品货号: CSP235
  • 货期: 现货
  • 价格与订购: 2880
  • 数量:
    库存: 100
  • 规格:
  • 产品信息
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    产品名(Product Name)
    Anti SARS-CoV-2(2019-nCoV) NSP3 polyclonal antibody
    货号(Catalog No.)
    CSP235
    描述(description)
    Produced in rabbits immunized with purified,Recombinant SARS-CoV-2 NSP3 protein
    特异性(Spcificty)
    Recognizes SARS-CoV-2 NSP3 protein
    亚型(Isotype)
    IgG
    克隆性(Clonality)
    Polyclonal
    别名(Alternative names)
    Non-structural protein 3,PL2-PRO,Papain-like proteinase,PL-PRO,Replicase polyprotein 1a
    偶连物(Conjugation)
    Unconjugate
    种属反应性(Species reactivity)
    Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
    应用实验(Tested applications)
    Elisa
    免疫原(Immunogen)
    Recombinant SARS-CoV-2 NSP3(Glu1024-Gln1198)
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    背景(Background)
    Responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PL-PRO possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Participates together with nsp4 in the assembly of virally-induced cytoplasmic double-membrane vesicles necessary for viral replication. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF3. Prevents also host NF-kappa-B signaling.
    状态(Form)
    Liquid
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    储存溶液(Buffer)
    PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
    应用实验及稀释比例(Dilution Range)
    Elisa:1:4000~1:8000
    浓度(Concentration)
    0.33mg/ml
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    分子量(MW)
    200kDa
    Accession #
    P0DTC1
    宿主(Host)
    Rabbit
    Note
    For research use only .