 |
Amily |
|
Emily |
|
Lily |
159-2642-3062
服务热线（工作日：9:00-17:30）
武汉科斯坦生物科技有限公司
热搜词：燕窝酸，不饱和脂肪酸，神经酰胺，花青素，黄酮，皂苷
Wuhan Chemstan Biotechnology Co., Ltd.
武汉科斯坦生物科技有限公司
-
在线咨询 -
官方邮箱 -
微信下单
-
回到顶部
代谢组学
科研服务
抗体/蛋白
地 址：武汉市东湖新技术开发区高新大道666号，武汉
国家生物产业基地B、C、D区研发楼C1栋
产品销售：15926423062
技术服务：18971263062
E - mail ：info@chemstan.com
邮 编：430075
化合物单体
科斯坦生物（Chemstan）所有产品和服务仅用于科学研究，不为任何个人或者非科研性质的用途提供产品和服务。
Copyright @ 武汉科斯坦生物科技有限公司.All rights reserved
网站建设：中企动力武汉鄂ICP备19006850号-1
浏览量:
产品名称：
Research Grade Narnatumab ( 那呐妥单抗 )
NO.
258
货号：
CSD00263
中文名称
那呐妥单抗
英文名词
Research Grade Narnatumab
CAS号
1188275-92-4
产品货号：
CSD00263
货期：
现货
价格与订购：
2480.00
数量：
-
+
库存：
100
产品信息
如何订购
货号（Catalog No.）icon
CSD00263
通用名INNicon
Narnatumab
纯度(Purity)icon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
产品描述(Description)icon
Narnatumab is under investigation in clinical trial NCT01119456 (A Study of IMC-RON8 in Advanced Solid Tumors).
别名(Alternative names)icon
IMC RON-8,RON8
靶点;物种(Specificity target name;species)icon
MST1R/CD136[Homo sapiens]
活性研究（体外/体内研究）(Activity in vitro)icon
LY2801653 demonstrates in vitro effects on MET pathway-dependent cell scattering and cell proliferation. It demonstrates more potent anti-proliferative activity in cell lines with MET gene amplification (MKN45, Hs746T and H1993) than the cell lines without MET gene amplification (U-87MG, KATO-III). LY2801653 also maintains potency against 13 MET variants, each bearing a single-point mutation. It is found to have potent activity against several other receptor tyrosine oncokinases including MST1R, FLT3, AXL, MERTK, TEK, ROS1, DDR1/2 and against the serine/threonine kinases MKNK1/2. The mean IC50 value of LY2801653 for inhibition of MET auto-phosphorylation in HGF-stimulated H460 cells is 35.2±6.9 nM and the IC50 for MET auto-phosphorylation in S114 cells is 59.2 nM.
种类(Species)icon
Homo sapiens
受体鉴定(Receptor identification)icon
IgG1-kappa
分子量(MV)icon
148000.00 Da
CASicon
1188275-92-4
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
上一篇
Research Grade Ficlatuzumab ( 非拉妥组单抗 )
Research Grade Ozoralizumab ( 奥利组单抗 )
下一篇