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  • 产品名称: Research Grade Erlizumab ( 厄利珠单抗 )
  • 产品货号: CSD00182
  • 货期: 现货
  • 价格与订购: 2480
  • 数量:
    库存: 100
  • 规格: 100μg
  • 产品信息
  • 如何订购
    货号(Catalog No.)
    CSD00182
    通用名INN
    Erlizumab
    纯度(Purity)
    >95%
    浓度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    内毒素(Endotoxin level)
    Please contact with the lab for this information.
    别名(Alternative names)
    rhuMAb
    靶点;物种(Specificity target name;species)
    ITGB2/CD18 [Homo sapiens]
    活性研究(体外/体内研究)(Activity in vitro)
    Leukadherin-1 pretreatment reduces secretion of interferon (IFN)-γ, tumour necrosis factor (TNF) and macrophage inflammatory protein (MIP)-1β by monokine-stimulated NK cells. It also reduces secretion of IL-1β, IL-6 and TNF by Toll-like receptor (TLR)-2 and TLR-7/8-stimulated monocytes. Leukadherin-1 modulates NK cell cytokine secretion and does not modulate Syk activation in NK cells. LA1 increases CD11b/CD18-dependent cell adhesion to fibrinogen with 50% effective concentration (EC50, the effective concentration for a 50% increase in adhesion) values of 4 μM.
    种类(Species)
    Humanized
    受体鉴定(Receptor identification)
    IgG1-nd
    分子量(MV)
    148000.00 Da
    CAS
    211323-03-4
    存储条件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .