Recombinant Human TMPRSS2 protein
>90% as determined by SDS-PAGE
Please contact with the lab for this information.
A DNA sequence encoding the human TMPRSS2 (Ser284-Gly492) was fused with His tag
Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
Please contact with the lab for this information
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
In general, proteins are shipped out with blue ice unless customers require otherwise.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.
Transmembrane protease serine 2,Serine protease 10.