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  • 产品名称: Recombinant Human CD147 protein
  • 产品货号: CSP00046
  • 货期: 现货
  • 价格与订购: 2880
  • 数量:
    库存: 100
  • 规格:
  • 产品信息
  • 如何订购
    产品名(Product Name)
    Recombinant Human CD147 protein
    货号(Catalog No.)
    CSP00046
    描述(description)
    Recombinant Human CD147 is produced by E.coli expression system and the target gene encoding Ala22-Ala207 is expressed with His Tag
    表达系统(Expression system)
    E.coli
    种属(Species)
    Homo sapiens (Human)
    Accession #
    P35613
    别名(Alternative names)
    5F7 Protein, Human; Basigin Protein, Human; CD147 Protein, Human; EMMPRIN Protein, Human; M6 Protein, Human; OK Protein, Human; TCSF Protein, Human
    预测分子量(Predicted Molecular Mass)
    22.59 kDa
    纯度(Purity)
    >90% as determined by SDS-PAGE
    内毒素(Endotoxin level)
    Please contact with the lab for this information
    制剂(Formulation)
    Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
    运输方式(Shipping)
    In general, proteins are shipped out with blue ice unless customers require otherwise.
    稳定性&储存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    复溶(Reconstitution)
    Please refer to the instraction in the hard copy of COA.
    应用(Application)
    Immunogen
    背景(Background)
    CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
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    Note
    For research use only .