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代谢组学
科研服务
抗体/蛋白
地 址:武汉市东湖新技术开发区高新大道666号,武汉
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产品名称:
Recombinant Human CD147 protein
NO.
062
货号:
CSP00046
中文名称
新冠相关蛋白
英文名词
Recombinant Human CD147 protein
CAS号
/
产品货号:
CSP00046
货期:
现货
价格与订购:
2880.00
数量:
-
+
库存:
100
产品信息
如何订购
产品名(Product Name)icon
Recombinant Human CD147 protein
货号(Catalog No.)icon
CSP00046
描述(description)icon
Recombinant Human CD147 is produced by E.coli expression system and the target gene encoding Ala22-Ala207 is expressed with His Tag
表达系统(Expression system)icon
E.coli
种属(Species)icon
Homo sapiens (Human)
Accession #icon
P35613
别名(Alternative names)icon
5F7 Protein, Human; Basigin Protein, Human; CD147 Protein, Human; EMMPRIN Protein, Human; M6 Protein, Human; OK Protein, Human; TCSF Protein, Human
预测分子量(Predicted Molecular Mass)icon
22.59 kDa
纯度(Purity)icon
>90% as determined by SDS-PAGE
内毒素(Endotoxin level)icon
Please contact with the lab for this information
制剂(Formulation)icon
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
运输方式(Shipping)icon
In general, proteins are shipped out with blue ice unless customers require otherwise.
稳定性&储存(Stability &Storage)icon
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
复溶(Reconstitution)icon
Please refer to the instraction in the hard copy of COA.
应用(Application)icon
Immunogen
背景(Background)
icon
icon
CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
icon
Noteicon
For research use only .
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