Recombinant Human ACE2 protein
Recombinant Human ACE2 is produced by Mammalian cells expression system and the target gene encoding Ser19-Asp615 is expressed with C-His Tag
NP_001358344.1 or Uniprot Q9BYF1
ACE-related carboxypeptidase,Angiotensin-converting enzyme homolog,Metalloprotease MPROT15
>90% as determined by SDS-PAGE
Please contact with the lab for this information
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
In general, proteins are shipped out with blue ice unless customers require otherwise.
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
Please refer to the instraction in the hard copy of COA.
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don’t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.icon