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产品名称:
Research Grade Aselizumab ( 阿塞珠单抗 )
NO.
179
货号:
CSD00177
中文名称
阿塞珠单抗
英文名词
Research Grade Aselizumab
CAS号
395639-53-9
产品货号:
CSD00177
货期:
现货
价格与订购:
2480.00
数量:
-
+
库存:
100
产品信息
如何订购
货号(Catalog No.)icon
CSD00177
通用名INNicon
Aselizumab
纯度(Purity)icon
>95%
浓度( Concentration)icon
1mg/ml
Formulationicon
PBS buffer PH7.5
Sourceicon
CHO cells
内毒素(Endotoxin level)icon
Please contact with the lab for this information.
别名(Alternative names)icon
HuDreg-55
靶点;物种(Specificity target name;species)icon
SELL/CD62L [Homo sapiens]
活性研究(体外/体内研究)(Activity in vitro)icon
Dexamethasone (Hexadecadrol) regulates several transcription factors, including activator protein-1, nuclear factor-AT, and nuclear factor-kB, leading to the activation and repression of key genes involved in the inflammatory response.
Dexamethasone potently inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) release from A549 cells with EC50 of 2.2 nM. Dexamethasone (EC50=36 nM) induces transcription of the β2-receptor is found to correlate with glucocorticoid receptor (GR) DNA binding and occurred at 10-100 fold higher concentrations than the inhibition of GM-CSF release. Dexamethasone (IC50=0.5 nM) inhibits a 3×κB (NF-κB, IκBα, and I-κBβ), which is associated with inhibition of GM-CSF release.
种类(Species)icon
Humanized
受体鉴定(Receptor identification)icon
IgG4-nd
CASicon
395639-53-9
存储条件(Storage)icon
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Noteicon
For research use only .
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