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- 产品名称: Research Grade Nofetumomab ( 诺非妥莫单抗 )
- 产品货号: CSD00063
- 货期: 现货
- 价格与订购: 2480
- 数量:
- 规格: 100μg
- 产品信息
- 如何订购
货号(Catalog No.)
CSD00063
通用名INN
Nofetumomab
纯度(Purity
>95%
浓度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
内毒素(Endotoxin level)
Please contact with the lab for this information.
产品描述(Description)
Technetium Tc-99m nofetumomab merpentan (Tc-99m nm) consists of a Fab fragment of an IgG2b of the pancarcinoma murine antibody NR-LU-10.1 The NR-LU-10 antibody is directed against a 40 kDa glycoprotein antigen expressed in a variety of cancers and some normal tissues.Label Tc-99m nm was developed by Boehringer Ingelheim Pharma KG and FDA approved on September 14, 1992. It was after discontinued on August 13, 2013, but in the 2018 FDA submission list, it can be found as a substance type II (Drug substance) with an active status.The mechanism of action in Tc-99m nm is ruled by the presence of nofetumomab, which can recognize the pancarcinoma antigen EpCAM and/or CD20/MS4A1,2 and merpentan,that acts as a linker for the binding of technetium.
靶点;物种(Specificity target name;species)
IL3RA/CD123[Homo sapiens]
种类(Species)
Humanized
受体鉴定(Receptor identification)
IgG1-kappa
CAS
165942-79-0
存储条件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .